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"Inner and outer peripheries in the regional development of the Czech Republic - from genetic determination to territorial cohesion". The project solved the definition of both types of peripheries, using the analysis of the socio-economic situation incl. Questionnaire investigation and the approach of individual regions to the closure of regional development from the point of view of the inner and outer peripheries. The outcome of the research consists in the formulation of methodology, measures and recommendations in the sense of strengthening the territorial cohesion of the Czech Republic. The project gradually fulfilled the objectives of the program with the help of a complex and multidisciplinary approach in the socio-economic analysis of the inner and outer peripheries, their borders, the analysis of development documents and recommendations for solving the development problems of the inner and outer peripheries, thereby strengthening the social and humanitarian dimension in the activities of this applied research and in application of the outputs of the activities listed below in the form of new or substantially improved applied research procedures. As part of the project, the socio-economic potential of the inner and outer peripheries was verified, while a draft measure was prepared for the development of these problematic, disadvantaged regions, including possible implementation and legislative provision of assistance to the peripheries across state and regional borders. The project monitored the necessity of coordinating socio-economic activities across regional borders, as most regional processes are more or less closed within regions. The peripheral areas of the regions are thus handicapped, as development impulses often do not arrive here or only weakly (later). Therefore, it is necessary that local actors (regions, municipalities) pay attention to the negative aspects conditioned by the geographical location at the regional border with the aim of strengthening territorial cohesion. When solving the project, the methodological procedures of several scientific disciplines were connected, namely regional studies, regional development, economic and social geography, the environment, sociology, law and political science. A comprehensive and multidisciplinary approach in the detailed socio-economic analysis of inner and outer peripheries (at the level of municipalities), their borders, analysis of development documents and recommendations for solving development problems of inner and outer peripheries is an innovation and a fundamental contribution. In principle, it is about using the potential of basic research, already a whole range of scientific disciplines, regional economics, socio-economic geography, sociology, political science and lawyers to applications for formulating a set of proposals, measures and recommendations, which, when used by the relevant authorities, could stimulate inter-regional cooperation and strengthen territorial cohesion of inner and outer peripheries. A relatively large solving team (10 people representing 4 workplaces) met regularly for meetings, either online meetings during the covid pandemic in approximately weekly/two-week cycles, as well as face-to-face meetings, including multi-day meetings in individual internal and external peripheries, where they were discussed in detail advances in research with a focus on the field research methodology, the methodology of evaluating the obtained data, the preparation of agreed outputs from the project and the formulation of partial outputs, as well as the specific/real issues of the respective model territories. During the research, more than 60 thematic maps based on socio-economic analysis were processed, at the level of all municipalities in the Czech Republic. It was on the basis of socio-economic analyzes that two essential maps were created in a creative way, namely the map of the inner peripheries and the map of the outer peripheries.